Metrogyl gel is a reliable product in dentistry
Metrogyl Denta is a dental medicinal product produced by pharmaceutical companies in the form of a gel. Thanks to the combined composition, including:
- antibiotic;
- antiseptic,
- the medicine has a wide spectrum of antimicrobial action and is recommended by experts for use by both adults and children over 6 years of age.
The main active ingredients of the drug are metronidazole and chlorhexidine.
Metronidazole, known for its antimicrobial properties, is successfully used in medicine for:
- peptic ulcers;
- chronic colitis;
- inflammation of the urinary system;
- genital infections,
- as well as for the purpose of preventing complications that often arise after surgery.
Chlorhexidine is an effective antiseptic used in medical practice:
- during preoperative treatment of hands;
- when cleaning medical premises;
- for disinfection of instruments.
Thanks to its gel consistency, Metrogyl is successfully used in dentistry, but in addition, the product can help solve some cosmetic problems and stop the inflammatory processes of the external genitalia.
Metrogil:
instructions for use
In dental practice, the drug is used to treat:
- gingivitis;
- periodontitis;
- bacterial stomatitis;
- lip inflammation;
- inflammatory processes of the hoods over wisdom teeth;
- inflammation of the mucous membrane;
- alviolite of the socket of an extracted tooth,
- It is also used as an additional agent in the treatment of periodontitis and periodontal abscess.
However, despite the effectiveness of Metrogyl, the instructions of which recommend its use for these diseases, an experienced doctor may prescribe other drugs, depending on the individual characteristics of the patient’s body and the complexity of the case.
Metrogyl denta goes on sale in laminated plastic tubes of 20 grams and is sold without a prescription.
Metrogyl, reviews of which from experts allow us to recommend to patients a relatively inexpensive and effective antiseptic drug, is often used as an everyday means of oral hygiene, which helps prevent many inflammatory processes.
Metronidazole denta gel for gums 20g
Metronidazole (in the form of metronidazole benzoate), chlorheskidine gluconate (in the form of 20% solution of chlorheskidine gluconate) gum gel, 20 g
Composition and release form
Metronidazole 1%, gel for gums, 20 g in a tube.
Pharmacological group:
Antimicrobial drug for topical use for diseases of the oral cavity; A01AB17.
pharmachologic effect
Antimicrobial drug for the treatment and prevention of infectious and inflammatory diseases of the oral cavity. Metronidazole is a nitroimidazole derivative that has antiprotozoal and antibacterial effects. The mechanism of action of metronidazole is the biochemical reduction of its 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group of metronidazole interacts with DNA in microbial cells, inhibiting synthesis from nucleic acids, which leads to the death of bacteria. The MIC50 of metronidazole is less than 1 μg/ml. Metronidazole Denta is active against anaerobic protozoa and bacteria that cause periodontitis: Porphyromonas gingivalis, Prevotella intermedia, Prevotella denticola, Fusobacterium fusiformis, Wolinella recta, Treponema spp., Eikenella corrodens, Borrelia vincenti, Bacteroides melaninogenicus, Selenomonas spp.
Indications for use
— acute gingivitis — acute necrotizing ulcerative gingivitis Vincent — chronic gingivitis (edematous, hyperplastic, atrophic /desquamative/) — chronic periodontitis — periodontal abscess — recurrent aphthous (ulcerative) stomatitis — toothache of infectious origin
Dosage regimen
The gel is applied to the gum area 2 times a day. After applying the gel, do not rinse your mouth or eat food for 15 minutes. To prevent the disease, a small amount of gel is added to the toothpaste. Preventive courses of treatment are carried out for 2-4 weeks 1-2 times a year.
Side effect
Possible: headache, metallic taste in the mouth, allergic reactions (skin rash, itching, urticaria). After topical use of Metronidazole Denta, systemic side effects are unlikely.
Contraindications
Hypersensitivity to the components of the drug and nitroimidazole derivatives
Pregnancy and lactation
The use of the drug during pregnancy and lactation is undesirable and is possible only if the expected benefit outweighs the risk of side effects.
special instructions
When applied topically, the concentration of metronidazole in the gum area is significantly higher than when metronidazole is taken orally, so prescribing Metronidazole Dent along with oral metronidazole allows you to reduce its dose and thereby minimize the risk of side effects. Avoid contact of the drug with the eyes. During the period of use of Metronidazole Denta, you should not drink alcohol, because... Metronidazole has the ability to cause disulfiram-like reactions.
Overdose:
Currently, no cases of overdose of Metronidazole Denta have been reported.
Drug interactions
When the drug is used topically, interaction with other drugs is minimal, but the possibility of such reactions cannot be completely excluded. The possibility of the following drug interactions should be considered. With simultaneous use, metronidazole enhances the effect of indirect anticoagulants. When metronidazole is used in combination with disulfiram, the toxicity of both drugs increases.
Pharmacokinetic interaction
Phenobarbital and phenytoin increase the metabolism of metronidazole, which leads to a decrease in its effect. Cimetidine inhibits the metabolism of metronidazole, which may lead to increased metronidazole serum concentrations.
Storage conditions
Store at room temperature, protected from light and out of reach of children.
Conditions for dispensing from pharmacies
Dispensed with a doctor's prescription.
Application benefits
Despite the rather low concentration of active substances and the lack of analgesic effect, Metrogyl Denta gel has a number of advantages over more modern drugs used in medicine, for example:
- the drug is perfectly fixed on the mucous membranes;
- has a fairly high efficiency,
- In addition, its affordable cost allows you to regularly use this product for preventive purposes.
The active components of the drug allow you to influence pathogenic microorganisms, but are not able to block mediators of inflammatory processes in tissues, therefore, in the treatment of many diseases, experts recommend combined procedures to achieve a more effective result.
Metrogyl Denta for stomatitis
Stomatitis is a fairly common pathology of the mucous membrane, occurring in both adult patients and children, however, Metrogyl is effective only for bacterial forms of the disease and when diagnosing them, the drug allows for healing.
To heal ulcers, in these cases, applications are recommended, but the drug is absolutely ineffective for stomatitis caused by viruses.
When treating gums, the drug is applied to the affected areas of the mucous membranes, for example, using cotton swabs. The course of treatment for stomatitis lasts for 7-10 days, procedures are carried out 2-3 times a day.
Alviolite therapy involves placing a small amount of gel into the inflamed hole.
When teething through wisdom teeth, it is recommended to use the drug as a toothpaste, applying the product to the inflamed gums. In this case, using a toothbrush with gel, both teeth and gums are treated, but you should refrain from eating and drinking for half an hour so that a protective film is formed that will protect the oral cavity from pathogenic microorganisms.
Metrogyl Denta: characteristics of the drug
This is a well-known medicine that helps in the fight against infectious and inflammatory diseases of the oral cavity. This product is sold over-the-counter in pharmacies.
Metrogyl Denta is a gel based on chlorhexidine and metronidazole. Chlorhexidine is an antiseptic that prevents the proliferation of pathological microorganisms on the mucous membrane. It is often used after surgery. Metronidazole is an active antibacterial agent widely used for periodontal diseases and oral mucosa.
Metrogyl Denta: how to use correctly
This drug, regardless of the inflammatory process in the oral cavity, is used according to the following scheme: apply a thin layer to the gums using a finger (after washing your hands) or a cotton swab - 2 times a day. After which it is not recommended to eat or drink for about 30 minutes. On average, the course of treatment is up to 10 days.
Metrogyl Denta: contraindications
The active substances included in this medicine have their own characteristic contraindications:
- allergic manifestations to metronidazole or chlorhexedine;
- diseases of the hematopoietic system;
- disorders of the nervous system;
- age under 18 years.
Therefore, before using this remedy, you need to consult a doctor.
Features of use
The use of Metrogil Dent gel, especially in the initial stages of treatment, can cause bleeding gums, increased swelling and burning. Such symptoms may appear within a few days, but if they continue, you should stop using the drug.
Despite the fact that no obvious contraindications or side effects have been identified for the drug, Metrogyl is not recommended for use for the treatment of:
- children under 6 years of age;
- women in the first trimester of pregnancy,
- In addition, it is not advisable to use the drug while breastfeeding and, if it is necessary to use it, you will have to stop breastfeeding.
Many experts recommend avoiding drinking alcohol during treatment with Metrogyl gel, since it contains an antibiotic that can be absorbed into the blood, even when applying applications.
In addition, the use of the drug should be discontinued at the first signs of intolerance to the drug.
Studies have shown a negative effect of the drug when taken together with anticoagulants, since the active substances of Metrogyl can enhance their effect, which can cause bleeding.
Experts recommend careful use of the drug, since, for example, swallowing the gel can have serious consequences:
- nausea;
- dizziness,
- which is facilitated by metronidazope, which is part of the product.
Metromezol-Dent dental gel 20g No. 1
Name
Metromezol-Dent gel ostomy in tubes 20g in pack No. 1
Description
gel from white to white with a yellowish tint of uniform consistency.
Main active ingredient
metronidazole
Release form
Gel
Dosage
20g
Indications for use
Infectious and inflammatory diseases of the periodontium and oral mucosa: acute and chronic (edematous, hyperplastic, atrophic) gingivitis; acute ulcerative-necrotizing gingivitis of Vincent; acute and chronic periodontitis; periodontitis, periodontal abscess (as part of combination therapy).
Directions for use and doses
Topically, for dental use only. The dose of gel on the gum area surrounding one tooth is a drop the size of a pea. For adults and children over 6 years old, with inflammation of the gums (gingivitis), the gel is applied to the gum area 2 times a day in a thin layer with a finger or a cotton swab; it is not recommended to wash off the gel. After applying the gel, you should refrain from drinking and eating for 30 minutes. The duration of treatment is on average 7–10 days. In case of periodontitis, after removing dental deposits, periodontal pockets are treated with gel and the gel is applied to the gum area. Exposure time – 30 min. The number of procedures depends on the severity of the disease. In the future, the patient can apply the gel independently, applying the gel to the gum area 2 times a day for 7–10 days. To prevent exacerbations of chronic gingivitis and periodontitis, the gel is applied to the gum area 2 times a day for 7–10 days. Preventive courses of treatment are carried out 2–3 times a year. In patients with impaired liver or kidney function, no dose adjustment is required. In elderly patients, no dose adjustment is required.
Contraindications
Individual intolerance to metronidazole, chlorhexidine, as well as nitroimidazole derivatives. Intolerance to any components included in the drug. Children's age up to 6 years.
Compound
each tube (20 g) contains: active ingredients: metronidazole – 200 mg, chlorhexidine digluconate (in the form of chlorhexidine digluconate 20% solution) – 10 mg; excipients: propylene glycol, carbomer 980, disodium edetate, sodium saccharin, levomenthol, sodium hydroxide, purified water.
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Instructions for use for Metromezol-Dent dental gel 20g No. 1