Scientists have figured out how to stop the spread of tumors at the cellular level


The main factors contributing to the development of edema – changes in the biochemical composition of blood plasma and tissue fluid, hormonal changes, increased capillary permeability, difficulty in the outflow of venous blood and lymph, impaired gas exchange and excretory function of the kidneys, congestion in heart failure, sedentary lifestyle and critical ischemia, when a person is in pain forced to sleep with one leg down.
True edema can be local and general. With general edema, fluid accumulates throughout the body; with local edema, it lingers on the diseased area of ​​the body. Each of these two species has many varieties. Let's look at the main ones.

Ways to get rid of bruises

Most often, the appearance of a bruise is preceded by a strong blow, which cannot be ignored. This injures small vessels, a small amount of blood flows out of them and permeates the subcutaneous tissue and lower layers of the skin. In response to injury, local swelling occurs - a protective reaction of the body. At this stage, the bruise is not yet visible, but you already need to take active action. The goal is to reduce tissue permeation with blood.

In order to quickly reduce swelling at the site of a bruise, it is necessary to use agents that cause vasospasm. Cooling with ice works well for this, but a frozen piece of meat wrapped in film and a thin towel will also work. It must be applied to the site of injury for 20 minutes. After cooling, the ice is removed, but the procedure can be repeated after 15-20 minutes. Constantly keeping the cold near the bruise is dangerous and can cause even more damage.

Home remedies can help relieve swelling. For this you can use:

  • a compress made from a solution of vinegar or vodka;
  • onion gruel with salt;
  • applying a cut aloe leaf;
  • half a raw potato.

Folk remedies against bruises can be used at an early stage, immediately after a bruise. A mixture of garlic and vinegar pulp and lavender essential oil, which should be applied to the injury site, are considered effective. But you need to be careful; minor bruises can be treated at home without the help of a doctor.

What to put on a bruise

In order for treatment for a bruise to be effective, it is necessary to take into account the time that has passed since the injury. The formation of a hematoma goes through several stages. Immediately after the injury, agents are used that relieve swelling. At home, at an early stage, you can use folk remedies, but after that, purchase pharmaceutical drugs.

On the first day, you can apply ointment or gel containing heparin to the bruise. It helps reduce swelling by increasing the speed of blood flow. Heparin is well absorbed through the skin, thins the blood and prevents the formation of a hematoma. Therefore, treatment of the bruise will proceed quickly.

But when using heparin, you need to remember that it is not recommended to use it in the first hour or two after a bruise. It can increase bleeding at the injury site and cause an enlarged hematoma.

If a soft tissue injury is accompanied by pain, it can be reduced with the help of non-steroidal anti-inflammatory drugs. Quickly relieve discomfort with a gel or ointment that contains diclofenac, ibuprofen or piroxicam. They can be applied to the impact site after a few hours.

After a day, these remedies for treating bruises are no longer effective. Blood permeates the tissues, coagulates, and its cells are destroyed. Therefore, the bruise turns blue due to the protein hemoglobin. From this moment, its disintegration and hematoma begins to bloom. She herself will not be able to pass in a short time until all hemoglobin is destroyed into bilirubin.

We need products that resolve bruises by heating the tissues and increasing blood flow in them. You can use dimethyl sulfoxide creams or ointments at home without a doctor's prescription. This substance is obtained from hot peppers, so it has a warming effect. Minor bruises after using it disappear within 2-3 days.

How to eliminate swelling after alcohol?

Having learned in detail about swelling after alcohol and how to get rid of it, you can ask yourself one more question. Is it possible to make it not appear at all? There is a certain list of measures that will minimize this risk. Although, of course, it cannot be completely excluded.

If you would like to avoid such a problem , you should follow these rules:

  • Choose alcohol of decent quality.
  • Do not eat salty foods at feasts.
  • Take contrast showers and drink mineral water before drinking alcohol, on the day of the upcoming event.
  • Use sorbents.
  • Do not drink alcohol if you experience frequent and severe swelling.

It is also worth following a light diet the day after drinking alcohol. This will also help the body recover faster. It is worth remembering that the most severe swelling occurs from beer. It’s also worth knowing that women are most prone to swelling. Thus, in former alcoholics, these manifestations do not go away even if they are coded and completely stop drinking.

Swelling can last a lifetime. And besides, this symptom may hide severe disturbances in the functioning of the body. If there is constant severe swelling, you should consult a doctor and undergo an examination. And it would be even wiser to reconsider your attitude towards alcohol and lifestyle.

How to quickly remove a bruise on your face

A black eye appears much faster than in other parts of the body. If measures are not taken quickly, the resorption of the bruise will take a long time. The reason is the location of the vessels and the loose subcutaneous tissue that surrounds the eyes. It easily becomes saturated with blood and swells.

First aid after injury is to apply ice to the face. Of the folk methods of struggle, it is necessary to use safe ones that will not irritate the mucous membrane of the eyes. Therefore, a paste of onion, vinegar or garlic will not work. But you can use:

  • raw potatoes;
  • parsley paste;
  • a piece of raw pineapple (not canned);
  • essential oils.

They are also treated with pharmaceuticals containing heparin, diclofenac and ibuprofen. Bruises on the face can be smeared with gel with troxevasin. It reduces swelling, pain, relieves inflammation, increases capillary tone and reduces their fragility. Troxevasin helps to quickly remove bruises and strengthen small blood vessels. It is recommended to use it 2-3 times a day.

If the bruise is large and does not want to dissolve, you can try to hide it with the help of cosmetics. Women apply a special color corrector to the defect on the face, which covers the blue tint, after which the skin is smoothed with foundation and powdered.

Scientists have figured out how to stop the spread of tumors at the cellular level

3404 06 August

IMPORTANT!

The information in this section cannot be used for self-diagnosis and self-treatment. In case of pain or other exacerbation of the disease, diagnostic tests should be prescribed only by the attending physician. To make a diagnosis and properly prescribe treatment, you should contact your doctor.


One of the biggest challenges in the fight against cancer is preventing metastasis, that is, preventing tumor cells from spreading to other organs. In a new study conducted on mice, scientists have successfully tested a promising new way to block this process.

A team of researchers from Switzerland has found a “barrier” that prevents the development and spread of tumor cells. It is based on the Activin B protein and the ALK7 receptor, a combination that appears to play a decisive role in the progression of tumor growth.

The study results show that Activin B and ALK7 create a signaling pathway that causes cancer cells to naturally destroy themselves (apoptosis) and prevent tumors from forming (oncogenesis) and spreading.

Despite the fact that tests have so far been carried out only on mice, there is reason for optimism - humans have a lot in common with these animals, especially when it comes to the development of cancer. The “barrier” being studied may become the basis for creating new methods of combating malignant tumors.

“This study confirms that apoptosis is an important barrier to tumorigenesis,” says study team member Douglas Hanahan of the Swiss Federal Institute of Technology in Lausanne.

To block the growth of a cancerous tumor, the ALK7 receptor and the Activin B protein need to work together. Researchers have found that when they are used alone, cancers can suppress ALK7 or Activin B to survive.

Special protein complexes “activins”, one of which is Activin B, play an important role in many processes in the body - they are involved in regulating cell growth and proliferation, in the metabolic process, in organizing the immune response and in regulating the menstrual cycle.

The team studied neuroendocrine pancreatic cancer and mammary cancer in mice. In addition, scientists examined patients (people) with various types of cancer and found an association between the presence of ALK7 and a lower likelihood of recurrence. They found that metastases do not develop longer in cases of breast cancer with high ALK7. This supports the idea that ALK7 and its partner Activin B may be important chemical agents in preventing metastasis, although more research will be needed before this finding can be put to practical use in cancer treatment.

The researchers note that the important role of ALK7 was previously difficult to determine, but now this receptor can confidently be added to our arsenal of potential weapons against cancer.

“Understanding how cancer cells manage to overcome the various safety checkpoints created by nature is an important step towards understanding the developmental biology and pathogenesis of the tumor process,” says one of the researchers, Iakovos Michael from the Swiss Federal Institute of Technology.

The study was published in Developmental Cell

.

08.05.2019

IMPORTANT!

The information in this section cannot be used for self-diagnosis and self-treatment. In case of pain or other exacerbation of the disease, diagnostic tests should be prescribed only by the attending physician. To make a diagnosis and properly prescribe treatment, you should contact your doctor.

How to quickly remove bruises on legs

First aid for a bruise on the leg is a cold compress. This can be done by soaking a cloth in water mixed with vinegar or alcohol. Due to rapid evaporation from the surface of the skin, they remove the tumor or prevent it from forming.

To avoid having to wait for the hematoma to heal, you need to lie down and raise your leg above the level of your heart. This will speed up the flow of blood from the limb and prevent it from swelling. Ointment with heparin, painkillers and troxevasin also effectively resolve the bruise.

There are hardware methods that help heal bruises. In cosmetology clinics they are treated with a laser. Irradiation of a tumor causes tissue heating and accelerates the breakdown of hemoglobin. You can remove a small hematoma at one time, but a large one will only change color. The disadvantage of this treatment is its high cost.

How to get rid of very severe swelling?

If severe, pronounced swelling of the entire body occurs, this is a very dangerous symptom. It indicates significant problems with the body and the need to be examined by a doctor. In order to relieve such swelling, you will have to carry out a whole range of measures. For detoxification, it would be better to choose Smecta or similar drugs. You also need to buy mineral water, preferably alkaline. It should be drunk in large quantities to speed up the process of getting rid of edema . You need to use mild diuretics and start moving moderately. Walking will provide just the right amount of exercise that will help the body better cope with the problem. And healthy sleep will also come in handy. It will help restore strength.

Medicines for bruises

Major injuries are accompanied by severe pain, which is difficult to relieve with local remedies. Therefore, soon after injury, you can take painkillers orally based on:

  • nimesulide;
  • diclofenac;
  • indomethacin;
  • ibuprofen;
  • ketorolac.

They help relieve pain, reduce swelling and inflammation.

Sometimes hematomas appear due to increased fragility of blood vessels, so it is necessary to use agents to strengthen the capillaries against them. Riboxin and complexes containing vitamin C and ascorutin help with this.

It is difficult to remove blueness under the eyes that is not associated with injury. It appears due to kidney pathologies or due to the proximity of blood vessels under the skin. In this case, it is necessary to eliminate the cause, apply cooling compresses before bed or apply special patches.

Swelling of the legs

Edema of the lower extremities forms after a long binge, leading to slow blood flow and thrombosis. The reasons are:

  • impaired blood supply due to the negative effect of alcohol on the structure of blood vessels;
  • uncomfortable position while sleeping. Alcoholics fall asleep in uncomfortable positions, which interferes with normal blood circulation.

Swelling of the lower extremities is rarely a sign of binge drinking. Basically, this symptom signals serious disorders in the functioning of the liver, thyroid gland, and kidneys. It is impossible to get rid of swelling of the legs using traditional methods. Complex treatment is required. It includes physiotherapy and drug therapy. If left untreated, swelling of the legs leads to gangrene, vein blockage, and thromboembolism.

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