Solcoseryl ointment for external use 20g

Compound

The composition of 1 ml of solution for injection includes 42.5 mg of the active substance solcoseryl (deproteinized dialysate from the blood of dairy calves) and water for injection as an auxiliary component.
1 g of eye gel contains 8.3 g of the active substance solcoseryl (deproteinized dialysate from the blood of dairy calves) and auxiliary ingredients: sodium carboxymethylcellulose, sorbitol, water for injection, benzalkonium chloride.

1 g of Solcoseryl ointment contains 2.07 mg of the active substance solcoseryl (deproteinized dialysate from the blood of dairy calves) and a number of auxiliary components: methyl parahydroxybenzoate, propyl parahydroxybenzoate, cetyl alcohol, cholesterol, white petrolatum, water for injection.

Dragee Solcoseryl

The next item on our list is dragees (tablets in a blister of 0.1, 0.2 or 0.04 g). This form of release of the drug is effective in the following cases:

• elimination of the consequences of bedsores, including necrosis of individual tissue areas;
• restoration of skin after burns and ulcers, healing after transplantation;
• for recovery after heart attacks and strokes, other cerebral circulatory disorders;
• during recovery from open and closed craniocerebral injuries.

It is used either in combination with topical medications or as the next stage of treatment. They drink pills three times a day. Single dose - 0.1 g.

pharmachologic effect

Solcoseryl is a medicine that affects mainly metabolic processes in tissues. They activate tissue metabolic processes, improve trophism and stimulate tissue repair and regeneration when exposed to damaging factors.

Solcoseryl in injection form belongs to the pharmacotherapeutic group of hemodialysates and hemofiltrates, ointment and jelly - to the category of drugs used to treat wounds and ulcers (including poorly healing ones), gel - to the category of drugs used to treat ophthalmological diseases.

Jelly Solcoseryl

Solcoseryl jelly is a highly effective remedy in the treatment of bedsores and ulcers, including trophic, diabetic, and atherosclerotic. It is also used for burns, including severe ones, covering a large area of ​​skin.

1. Before applying the jelly, the surface is treated and cleaned.
2. The procedure is carried out twice a day.
3. After epithelization of the surface, it is recommended to use ointment.
4. Using jelly is effective only in the early stages.

Pharmacodynamics and pharmacokinetics

The main component of Solcoseryl preparations are fractions of the blood of calves with natural low-molecular substances included in their composition, the molecular weight of which does not exceed 5000 daltons.

To date, its properties have only been partially studied. In vitro tests, as well as preclinical and clinical studies, have shown that calf blood extract:

• promotes the restoration and/or maintenance of aerobic metabolism and oxidative phosphorylation processes, and also ensures the replenishment of cells that do not receive sufficient nutrition with high-energy phosphates;
• in vitro enhances the utilization of oxygen and activates the transport of glucose into tissues and cells suffering from hypoxia and metabolically depleted;
• helps improve repair and regeneration processes in damaged tissues that do not receive sufficient nutrition;
• prevents the development or reduces the severity of secondary degradation and pathological changes in reversibly damaged cells and cellular systems;
• in in vitro models activates collagen synthesis;
• has a stimulating effect on the proliferation (reproduction) of cells and their migration (in in vitro models).

Thus, Solcoseryl protects tissues that are in a state of oxygen starvation and nutritional deficiency, and accelerates the processes of their restoration and healing.

Solcoseryl eye gel is a dosage form that was developed specifically for the treatment of damage to the stroma of the cornea.

The gel-like consistency of the product ensures its uniform distribution on the cornea, and good adhesive properties allow it to remain on it for a long period of time. The use of eye gel accelerates the restoration of damaged tissues and prevents scarring.

The rate and extent of absorption, distribution, as well as the rate and route of elimination of the active substance from the patient’s body cannot be determined using conventional pharmacokinetic methods, since protein-free calf blood extract has pharmacodynamic effects that are characteristic of molecules with different chemical and physical properties.

In the process of studying the pharmacokinetic characteristics of Solcoseryl solution in animals, it was found that after a bolus injection, the effect of the drug develops within half an hour. The effect lasts for three hours after administration of the solution.

Indications for use

Solcoseryl injections - what are they for and what groups of patients are they prescribed for?

Solcoseryl in ampoules is indicated for patients who have been diagnosed with occlusive peripheral artery disease of the third or fourth degree according to the Fontaine classification and who have contraindications or intolerance to other vasoactive drugs.

It is also prescribed to patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , as well as to patients with disorders of cerebral metabolism.

What is Solcoseryl ointment and jelly for?

The use of ointment and jelly is advisable for the treatment of minor injuries (for example, abrasions or cuts), frostbite, first and second degree burns (thermal or solar), difficult-to-heal wounds (for example, trophic skin disorders of venous etiology or bedsores ).

Indications for use of eye gel

Solcoseryl eye gel is recommended:

• for the treatment of mechanical injuries and erosive damage to the cornea and conjunctiva;
• to accelerate the healing processes of postoperative scars in the postoperative period (for example, after a cornea transplant, surgery to remove a cloudy lens, surgical treatment of glaucoma , etc.);
• for the treatment of burns of the cornea of ​​various origins (thermal, chemical or radiation);
• for the treatment of ulcerative lesions of the cornea and keratitis of various etiologies;
• for dystrophic lesions of the cornea of ​​various etiologies, including neuroparalytic keratitis , endothelial-epithelial dystrophy ( bullous keratopathy ), etc.;
• for the treatment of corneal xerophthalmia with lagofatalmos (non-closure of the palpebral fissure);
• to improve the tolerability of contact lenses and reduce the time of adaptation to them.

Indications for use of Solcoseryl dragees

The drug in the form of pills is taken to treat trophic and radiation ulcers , bedsores , gangrene , and chronic venous insufficiency . They are also prescribed to patients with gastric and duodenal ulcers and to patients who require skin and/or corneal grafting procedures.

Solcoseryl ointment

Sometimes people wonder what is better - ointment or gel? The fact is that the ointment is used when the wound is dry. It also helps well with thermal damage to the skin - frostbite and burns of I and II degrees. It makes sense to use it to treat ulcers affecting large veins. Before using Solcoseryl, surfaces are treated with an antiseptic, since the ointment itself does not have an antibacterial effect. The ointment should be applied to the entire affected area, including healing areas. This should be done 2-3 times a day until the skin is completely restored.

When treating purulent inflammations and trophic ulcers, it is recommended to first surgically remove the pus, and then carry out therapy using not only ointment, but also injections.

Contraindications

Administration of the solution is contraindicated in patients with known hypersensitivity to calf blood dialysates. The solution is also contraindicated for atopy and for persons allergic to milk.

Since the ointment, jelly and solution contain derivatives of parahydroxybenzoic acid , which are used as preservatives, as well as trace concentrations of benzoic acid in free form, it is not used in the presence of allergic reactions to the above substances.

Ointment and jelly should be prescribed with caution to persons with a predisposition to allergic reactions.

A contraindication to the use of eye gel is hypersensitivity to its components. Since the eye gel can cause temporary visual impairment, you should not drive a car or operate potentially dangerous machinery for half an hour after its use.

Side effects

Administration of Solcoseryl IV or IM in very rare cases (their frequency does not exceed 0.1%) provokes the development of allergic or anaphylactic reactions, which are most likely caused by class E immunoglobulins.

If body temperature rises, urticaria , swelling and hyperemia at the site of drug administration, the use of Solcoseryl is stopped, and symptomatic treatment will be prescribed to eliminate the symptoms that appear.

Since the solution contains potassium, its administration may cause pain at the injection site.

When using Solcoseryl cream, a short-term burning sensation may be felt at the site of application. Discontinuation of the drug is required only in cases where the unpleasant sensation does not disappear for a long period of time.

In isolated cases, the use of jelly and ointment can cause the development of allergic reactions. If allergy symptoms appear, the use of these products should be discontinued.

Toxicological studies of Solcoseryl eye gel have shown the high safety of this drug when used for its intended purpose in accordance with the instructions.

After instillation of the product, a short-term burning sensation and mild irritation may be observed, which are not reasons for stopping treatment. Repeated instillations in rare cases provoke the development of allergic reactions (a similar effect is also observed during treatment with other ophthalmic drugs for topical use).

Instructions for use of Solcoseryl (Method and dosage)

Solution for injection, instructions for use

In cases where the patient's condition allows, the drug is recommended to be used in the form of an injection solution diluted at least 50:50 with saline or glucose solution.

Solcoseryl in ampoules is intended for slow administration in the form of intravenous injections or infusions. If intravenous administration is not possible, the drug can be injected into the muscle.

Since the drug in its pure form is a hypertonic solution, it should be administered slowly.

For intravenous infusion, the drug should be pre-diluted with 0.25 l of 0.9% NaCl solution or 5% glucose solution. Solcoseryl solution is administered intravenously by drip. The rate of administration depends on the hemodynamic status of the patient.

Patients with occlusive disease of peripheral arteries of the third or fourth degree according to the Fontaine classification are shown daily injection into a vein of 0.85 g (or 20 ml of undiluted solution) Solcoseryl.

The duration of use is usually up to four weeks and depends on the clinical situation.

Patients with chronic venous insufficiency , which is accompanied by the formation of treatment-resistant trophic ulcers , are indicated for intravenous administration of 0.425 g (or 10 ml of undiluted solution) Solcoseryl three times a week.

The duration of the course of treatment should not exceed four weeks (it is determined depending on the nature of the disease).

To prevent the appearance of peripheral venous edema , therapy is supplemented by applying a pressure bandage using an elastic bandage. If the patient has skin trophic disorders, treatment is carried out by combining injections or infusions of Solcoseryl solution with the use of jelly, and then ointment.

Patients who have suffered ischemic or hemorrhagic stroke are prescribed daily intravenous administration of 0.425 or 0.85 g of Solcoseryl (10 or 20 ml of undiluted solution) as the main course. The duration of the main course is 10 days.

Further treatment involves daily administration of 85 mg (or 2 ml of undiluted solution) Solcoseryl for one month.

In severe forms of brain contusions, daily injection of 1000 mg of Solcoseryl into a vein (corresponding to 23-24 ml of undiluted solution) is prescribed for 5 days.

The drug is administered intramuscularly undiluted at a dose of 2 ml/day.

Solcoseryl jelly and ointment: instructions for use

Cream and ointment are intended for application directly to the wound surface. Before using these dosage forms, the wound is first cleaned using a disinfectant solution.

Patients with trophic ulcers , as well as in cases of purulent infection of wounds, require preliminary surgical treatment before starting treatment.

When using jelly and ointment for frostbite , as well as for treating ulcers and skin injuries, it is important to remember that only sterile dressings should be used to treat damaged areas.

The gel is intended for application to fresh (including wet) wounds and weeping ulcers. The product is applied in a thin layer to a previously cleaned wound surface two or three times a day.

To treat areas where epithelization has begun, the use of ointment is indicated. The use of jelly is advisable until pronounced granulation tissue begins to form on the damaged surface of the skin and the wound begins to dry out.

The ointment is used primarily to treat dry wounds. The product is applied in a thin layer to a previously cleaned wound surface once or twice a day. If necessary, cover the treated surface with a bandage.

The course of treatment with the drug in this dosage form continues until the wound heals and is completely healed with elastic tissue.

For patients with severe trophic damage to the skin and soft tissues, it is recommended to combine jelly and ointment with the injection form of Solcoseryl.

Experience with the use of jelly and ointment for children is limited.

The drug does not have such release forms as suppositories. However, in the complex therapy of chronic colitis (inflammation of the colon), microenemas with Solcoseryl jelly are often prescribed.

Before use, the jelly contained in the tube (all 20 g) is added to 30 ml of warm water and after the enema procedure, which is carried out to cleanse the intestines, it is administered daily for 10 days.

Solcoseryl eye gel, instructions for use

Unless otherwise instructed by the attending physician, the eye gel is instilled into the conjunctival cavity, one drop three or four times a day. It is recommended to use the product daily until complete recovery.

In particularly difficult cases, eye ointment can be used one drop per hour. If the patient is simultaneously prescribed eye drops and Solcoseryl eye gel, the gel should be applied approximately half an hour after the drops.

During the period of adaptation to contact lenses, the drug is instilled into the conjunctival cavity immediately before installing the lenses and immediately after removing them.

Dragee Solcoseryl: instructions for use

The instructions recommend taking 100 mg tablets three times a day.

Infusion Solcoseryl

This form is effective in the treatment of burns, ulcers and wounds, the healing of which is difficult for various reasons. Infusions are also used to eliminate intoxication of the body and remove a person from alcoholic delirium. For each patient, the dosage is selected depending on the condition. The classic option is several procedures per week. Inject from 250 to 500 ml into a vein or artery at a rate of 20 to 40 drops per minute.

However, Solcoseryl should not be mixed with other drugs. Each bottle can only be used once after opening.

special instructions

Studies regarding the safety of using Solcoseryl solution for the treatment of children have not been conducted, therefore the drug is not recommended for the treatment of children under the age of 18 years.

Experience in treating children with the use of eye gel and topical dosage forms of the drug is also limited.

Solcoseryl in ampoules should be administered separately from other drugs (it is especially incompatible with phytoextracts). The exceptions are isotonic 0.9% NaCl solution and 5% glucose solution. It is also not recommended to dilute the product in potassium-containing solutions for infusion.

Eye gels are characterized by the ability to stick to contact lenses, so it is recommended to stop wearing lenses during treatment with the drug.

If allergic reactions associated with the use of the drug occur, you should immediately report them to your doctor. If the drug is used to treat an infectious disease of the cornea, therapy is supplemented with the prescription of appropriate antimicrobial agents.

Avoid contact of the gel with soft contact lenses as it may discolor them.

If necessary, treatment with Solcoseryl can be supplemented with antibacterial, vasodilating and other drugs.

Solcoseryl in cosmetology: for the face, hands, rough elbows and heels, for the skin around the eyes

In medicine, Solcoseryl preparations are used to accelerate the healing of damaged skin; in home cosmetology, they are used as a remedy for acne, stretch marks, and wrinkles. They are used to soften the skin, increase its turgor, improve complexion and eliminate acne .

In cosmetology, the ointment can be used as a stand-alone product (it is applied pointwise to problem areas, in the form of a mask once a week before bedtime and two to three times a week on the skin around the eyes), or in combination with other products, in particular with the drug Dimexide . Let's look at how to use these medications together.

For the face, Dimexide and Solcoseryl are used as follows: on the face, neck and décolleté, previously cleaned with peeling agents (you can also do alkaline peeling using tar soap, salt and soda), apply a solution of Dimexide with water, prepared in a ratio of 1:10 (enough dilute 5 ml (teaspoon) of Dimexide in 50 ml of water); Before the product has time to be absorbed, Solcoseryl ointment is applied to it in a thick layer.

If the gel is used in cosmetology, then the mask should be periodically sprayed with thermal water (you can also use regular water through a spray bottle). The mask is left on the face for about half an hour to an hour, then washed off and a light hypoallergenic cream is applied to the skin.

According to women who have tried this mask recipe on themselves, Solcoseryl ointment is more comfortable for the face than gel (after application, you don’t have to wash it off, just remove the residue with a napkin). In addition, it is not recommended to use a gel mask more than once a month.

Used as a remedy for wrinkles around the eyes, Solcoseryl ointment has proven itself to be a very effective remedy. Applying it like a regular cream, within a week you can see that the number of wrinkles and wrinkles has decreased, the skin has tightened and smoothed, and its color has become fresher and healthier.

Dimexide and Solcoseryl are no less effective against wrinkles, and perhaps even more effective. This is due to the ability of Dimexide to enhance the penetration of the active substance of drugs deep into the tissue. After using these products in combination, skin irregularities and imperfections disappear, and the effect of the mask is comparable to the effect of Botox .

The gel and ointment can also be used to soften rough skin on the elbows and heels. It is best to apply them to problem areas before bed.

Solcoseryl eye gel

The eye gel has proven itself to be excellent. This ophthalmic drug is used in the following cases:

• recovery from eye surgery, including laser vision correction, keratoplasty, glaucoma treatment and cataract removal;
• recovery after radiation, ultraviolet, chemical, thermal and other injuries and burns of the cornea;
• in the complex treatment of fungal, bacterial or viral keratitis;
• for corneal ulcers;
• for various forms of corneal dystrophy;
• to reduce the time it takes to get used to contact lenses.

Solcoseryl gel is very easy to use. It is necessary to instill the gel into the eye conjunctival sac. 1 drop 4 times a day is enough. If we are talking about serious diseases and injuries of the eye, the procedure is repeated every hour.

When getting used to hard lenses, you can apply a small amount of gel directly to the lens before putting it on. After you remove it, one drop is instilled into the conjunctival sac. If we are talking about soft lenses, then they do not need to be wetted. The gel is dripped directly into the eye before going to bed, when the lenses are removed.

The big advantage of this form is that it goes well with a large number of remedies for the treatment of eye diseases. The main condition for use is a gap of 15-20 minutes between the use of drugs. First, the main remedy is used, then Solcoseryl. This is necessary to ensure that the metabolites contained in calf blood do not interact with various antiviral drugs, such as acyclovir.

Analogues of Solcoseryl

• Aekol
• Acerbin
• Bepanten
• Shostakovsky Balm
• Wundehill
• Depanthol
• Contractubex
• Pantekrem
• Pantexol Yadran
• Panthenol
• Pantestin
• Hepiderm Plus
• Echinacin Madaus

Reviews of Solcoseryl

Almost all reviews left on the forums about injections, eye gel, jelly and Solcoseryl ointment are positive. Rare negative reviews are due largely to the fact that the drug provoked allergic reactions associated with intolerance to its active component.

Reviews of Solcoseryl gel and the drug in the form of an ointment allow us to conclude that these drugs effectively cope not only with minor scratches and minor burns, but also help cure difficult-to-heal wounds and ulcers.

The effectiveness of the ointment in cosmetology is also highly appreciated. Reviews of Solcoseryl ointment for the face indicate that this is truly an indispensable product for those who want to quickly get rid of wrinkles, acne, and simply improve the color and tone of the skin.

Gel is no less effective against wrinkles, but cosmetologists believe that it should not be used as part of masks too often (optimally - once a month). The ointment can be used as a regular cream.

The effectiveness of Solcoseryl against wrinkles increases when combined with Dimexide , which is due to the latter’s ability to improve the penetration of the active substance deeper into the skin.

The use of Dimexide and Solcoseryl in cosmetology

Is Solcoseryl effective in cosmetology? The question is ambiguous. It is actively used with other substances. The most popular complex remedy is the combination with Dimexide. Usually beauty requires sacrifices, including financial ones. But not in this case. Both substances are commercially available and inexpensive. However, it should be remembered that such a compound can theoretically cause allergies. Therefore, you should not take risks and immediately apply it to your face. A standard elbow bend test will let you know if this option is right for you. If yes, then you have saved a lot of money on various procedures performed in salons. Today, many experts recommend Solcoseryl for wrinkles as a replacement for expensive drugs.

Making a face mask is simple. You must first dissolve 5 ml of Dimexide in 1/3 cup of boiled water. Wipe your face with the resulting solution. Now Solcoseryl should be applied to it. Leave the mask for an hour, but do not forget to spray it with water so that it does not harden. To remove, use a regular damp swab and then a night cream. Small wrinkles really smooth out after this.

Recipes for hair using solcoseryl:

Will this substance help with deep wrinkles on the face? The effect of it is about the same as that of any other cream. There is no miracle and there never will be. The reason for the “bummer” lies in the fact that the drug does not penetrate through the dense layers of healthy skin. Its main purpose is wounds and ulcers that do not have any protective covering. The molecules of the compounds included in the composition are too large to penetrate too deeply. Moreover, if you have oily skin, you will only make things worse. What do the “experts” say? They refer to the fact that Dimexide performs the transport function. Is it so? No, he cannot perform a miracle in the spirit of Moses. Therefore, the molecules could not penetrate deep into the tissues and still cannot. Perhaps this “canard” was started by sellers or someone else.

By the way, it is generally better not to apply Dimexide to the skin of the face. When using it, dermatitis, itching, swelling and other unpleasant consequences often occur. Not to mention the nasty smell. It is unlikely that you will be able to sit with such a mask on your face, breathing calmly through your nose.

Solcoseryl price, where to buy

The price of Solcoseryl gel 20 g in Russia is about 2,600 rubles.

The average price of Solcoseryl in ampoules of 5 ml No. 5 in Ukrainian pharmacies is about 500 hryvnia.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

LuxPharma* special offer

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