Ketanov - an indispensable helper for toothache or a gentle killer?

Ketanov is considered one of the most powerful remedies in the fight against toothache. It allows you to relieve even severe sensations of discomfort in various dental diseases and is a structural analogue of Ketanov. The drug allows you to reduce the severity of symptoms of periodontitis, pulpitis, the pain from which prevents a person from leading a normal lifestyle. However, for chronic dental disorders, preference is given to other painkillers, since Ketanov has too large a list of contraindications and side effects.

Release form and composition

Ketanov is available in several pharmacological forms: tablets and solution for intramuscular administration. The tablets are white and round in shape. On one of their surfaces there is an engraving KTV. Ketanov tablets are available in cardboard packages containing 1, 2, 3 or 10 blisters.

The injection solution has a pale yellow tint and is used to quickly relieve unbearable pain. Typically, treatment with the drug in this form of release is carried out in hospitals. The liquid for injection is packaged in ampoules of 1 ml each. The ampoules are placed in cardboard packaging and sold in packs of 5 or 10 pieces.

The main substance in the solution and tablets is ketorolac trometamol. Auxiliary components in the tablets:

• starch;
• magnesium stearate;
• silicon dioxide, etc.

In addition to the active ingredient, the injections also include:

• purified water;
• ethanol;
• disodium edadate.

Before taking Ketanov, it is very important to study the instructions for use in order to exclude allergic reactions to its substances in its composition. Auxiliary components do not have an analgesic or anti-inflammatory effect. They are necessary in order to give the drug a certain shape and consistency and increase its shelf life.

How many minutes does it take for ketanov to take effect?

How many minutes does it take for ketanov to take effect?
Ketanov is a pain reliever, it begins to act in 15-20 minutes and for 6 hours ketanov stays in the body, relieving pain, all this time the person does not feel pain.

Ketanov has a side effect - drowsiness and stress on the liver and heart.

Ketanov should not be taken for more than 5 days, especially for older people, it increases blood sugar, but for many Ketanov is an effective salvation from severe pain.

My husband took it for toothache. It helped him within 15-20 minutes. And it worked for 5-6 hours, well, at least the tooth didn’t hurt for that long, and then everything started all over again. After 3 days, Ketanov stopped helping.

I take ketans for painful “critical days”, it helps very well. The pain disappears after 15-20 minutes, which is very convenient during an intense pace of life. You just can’t mix it with alcohol, it can have very negative consequences for the body. A friend took this drug for migraines, including, and says that it is an extremely effective remedy.

quot;Ketanovquot; - one of the most powerful painkillers. Its active ingredient is ketorolac, which is compared to morphine in its analgesic effect. This drug can be administered either intramuscularly or orally. It is clear that the goal is achieved more quickly when administered intramuscularly.

So, the official instructions indicate that the analgesic effect of the injection of quot;Ketanovquot; achieved in thirty minutes. And when taken per os (by mouth), this effect is achieved within one hour. That is, in thirty to sixty minutes.

I read the answers from my colleagues and I think that there is probably a personal sensitivity of the body, since everyone talks so unanimously about the pain-relieving effect after just fifteen to twenty minutes.

The medicine lasts up to six hours, so it is prescribed four times a day for intense pain.

During pregnancy, during breastfeeding, children under sixteen years of age, with liver failure and some other diseases quot; Ketanovquot; contraindicated.

The drug is dispensed in pharmacies with a doctor's prescription.

You can read the instructions here.

On the Internet I found a comment from a professional dentist (well, there probably aren’t any others, though.) in general, the maximum tablets are quot; Ketanovquot; They begin to act in thirty minutes, I can say for myself quot; Ketanovquot; It works faster, the tooth hurt and the pain went away in ten to fifteen minutes.

The painkiller Ketanov has a wide spectrum of action, quickly dulling almost any pain. This drug begins to act within 15-30 minutes . Ketanov very effectively relieves dental, menstrual, cancer, intestinal, and postoperative pain. But you need to take it with caution, not exceeding the daily dose, do not mix it with alcohol and use it with other medications, without a doctor’s indication.

Ketanov is a drug that is sold in pharmacies without a prescription and is a pain reliever. It begins to be absorbed in the stomach after its consumption and the result will be analgesic in twenty minutes, and the effect lasts for about five to six hours.

But this drug is not suitable for everyone; it has severe side effects. For those people who have diabetes, this drug is also not suitable.

And if the pain is severe, then it is better to inject this remedy. But this drug should not be taken for longer than five days. Its effect is lost and the body gets used to it. This medicine puts a lot of stress on the liver.

quot;Ketanovquot; has a fairly strong analgesic effect. Typically, medical professionals claim that the drugs begin to work within 30 minutes after administration. But quot; Ketanovquot; Personally it works faster for me. After taking the tablet quot; Ketanovquot; I started to feel relief from toothache literally within 10 minutes.

The drug quot;Ketanovquot; begins to have its effect no later than 40 minutes from the moment of administration. Although in practice, my personal experience suggests that after taking the quot; Ketanovaquot; — the pain begins to subside after 15-20 minutes (this drug saved me from the torment that I had during toothache).

quot;Ketanovquot; good pain reliever. This drug is available in tablets and ampoules for injection. The tablets begin to act within 15-20 minutes, injections act faster within 5-7 minutes after administration of the drug.

Action

The drug has a complex effect on the human body:

• anti-inflammatory;
• antipyretic;
• painkiller.

The medicine does not affect the central nervous system of patients and their moral state. The active component begins to act immediately after entering the blood. It stops the production of prostaglandins, which are responsible for the perception of pain. After taking the tablets or administering the solution, a person ceases to feel not only toothaches, but also spasms of other localizations.

The effect of taking Ketanov is observed after 30-40 minutes and lasts for 5-8 hours. How long it takes for Ketanov to take effect largely depends on its release form, the intensity of pain in a person and the patient’s individual susceptibility to medications.

The components of the drug are excreted along with urine, so it is not recommended to drink it for people who have problems with kidney function. Ketanov is excreted in the urine in the form of metabolites.

The benefits of the drug Ketanov

Still, before taking an analgesic drug, it is worth finding out what effect it has on the body.

In addition to pain relief, Ketanol has antipyretic and anti-inflammatory effects.

According to the characteristics in the instructions for use, the drug can have antipyretic, anti-inflammatory and analgesic effects. Therefore, many patients use this medicine not only for toothache, but also to alleviate the condition of various disorders and disorders of other organs. In addition, the drug Ketanov is able to eliminate the discomfort that occurs with diseases such as pulpitis and periodontitis.

After using the drugs, people do not feel drowsiness, fatigue, or lethargy. If after use there is no physical pressure on the affected area, the pain will go away after some time. Usually the pain completely disappears after 1-2 hours.

Advantages

The positive qualities include the following features of the drug Ketanov:

• This drug can eliminate painful sensations that are of high intensity
• Helps even in situations where other analgesics are powerless
• Compared to other painkillers, it has minimal side effects
• Long-lasting analgesic effect from 6 to 8 hours
• Subject to abrupt cancellation
• Non-addictive, even with prolonged use for 6 months

Indications for use

Among the dental indications for taking the drug, the following should be noted:

• tooth extraction and treatment;
• implantation;
• prosthetics;
• inflammation of the nerve ending of the tooth;
• cyst;
• advanced forms of caries;
• flux;
• periodontal disease.

The tablets also help with muscle pain and headaches. Other indications for their use:

How to relieve toothache

• otitis;
• tumor processes;
• pain after childbirth;
• hepatic colic;
• muscle spasm;
• osteochondrosis;
• radicular syndrome;
• osteoarthritis and osteoarthritis;
• pinched sciatic nerve.

Advantages

Ketanov has a powerful anesthetic effect for toothache, which lasts for a long period of time. Among NSAIDs, you cannot find another drug with a similar effect. A person can achieve a more pronounced therapeutic effect only by taking steroid painkillers. For this reason, Ketanov is prescribed even for unbearable toothaches associated with postoperative complications and traumatic factors.

Blocking prostaglandins also makes it possible to stop signs of inflammation and fever.

The therapeutic effect of Ketanov is equal to the drug Nise

Ketanov can be included in the list of the best painkillers because it:

• does not affect the cells of the central nervous system;
• does not provoke digestive disorders in the form of vomiting and stool disorders;
• does not increase heart rate;
• is not addictive;
• relieves severe pain, in which other NSAIDs are powerless;
• has a long-lasting analgesic effect (up to 8 hours);
• dispensed without a doctor's prescription;
• affects pain of various localizations.

Contraindications

Despite its effectiveness and long-lasting effect, the use of Ketanov is prohibited for people intolerant of its auxiliary and active substances and with certain types of diseases:

• chronic renal and liver failure;
• decompensated heart failure;
• exacerbation of gastrointestinal pathologies (ulcers, gastritis);
• disorders of the circulatory system;
• polyps and malignant formations in the nasopharynx.

Drink Ketanov with caution:

• with a low number of platelets in the blood;
• diabetes mellitus;
• rheumatoid disorders;
• sepsis;
• hypertension.

The drug is not recommended for pregnant and lactating women. Its active substance can be absorbed into breast milk and have a negative effect on children.

The tablets have age restrictions. They are not recommended for use by persons under 12 and over 65 years of age.

Reception scheme

For toothache Ketanov take 1 tablet per day. It does not matter when the drug is taken (before or after meals). Also, the period of time that has passed since the next meal does not matter. If the pain worsens again, then you need to take another tablet after 5-6 hours. If the doctor has allowed children under 12 years of age to take tablets, then a single dosage of the drug for this category of patients will not exceed ½ tablet.

The solution is administered intramuscularly only to those patients who have reached 16 years of age. It is allowed to use no more than 2 ml of solution at a time. For people with kidney pathologies and older people, the maximum dosage of Ketanov does not exceed 1 ml. The interval between injections is also 5-6 hours.

The frequency of taking the medication depends on the severity of pain symptoms:

• for moderate pain, take 1 tablet every 12 hours;
• for acute unbearable spasms, consumption of 4 capsules per day is allowed.

Despite the fact that Ketanov has a powerful effect, after its consumption it is not recommended to exert mechanical force on the tooth. Otherwise, the pain syndrome may worsen again. Also, you should not take the drug immediately before going to the dentist. It can distort the clinical picture of the disease (for example, when determining the stage of caries) and contribute to the incorrect diagnosis.

The drug should be discontinued on day 5. Failure to comply with this rule increases the likelihood of developing side effects from the gastrointestinal tract. It is necessary to consult a doctor for toothaches even if Ketanov has completely relieved the pain symptoms. There is a high probability that the symptom will make itself felt in the near future with greater intensity.

The drug in the form of a solution is rarely used to eliminate symptoms of dental problems. It is used to relieve muscle spasms. You can learn more about the methods of administering the solution in the instructions for use.

Instructions for use of KETANOV

The maximum duration of treatment should not exceed 5 days.

Gastrointestinal bleeding, ulceration and perforation

Gastrointestinal bleeding, ulceration or perforation, which may be fatal, has been reported with the use of NSAIDs at any time during treatment, with or without warning symptoms or in the case of a history of severe gastrointestinal disorders. The risk of severe gastrointestinal bleeding depends on the dosage of the drug. This particularly applies to elderly patients who use ketorolac at an average daily dose of more than 60 mg. For these patients, as well as for patients who are concomitantly using low doses of acetylsalicylic acid or other drugs that may increase gastrointestinal risk, combination treatment with protective agents (eg, misoprostol or proton pump inhibitors) should be considered. Ketanov is used with caution in patients who are concomitantly receiving drugs that may increase the risk of ulceration or bleeding, such as oral corticosteroids, selective serotonin reuptake inhibitors, or antiplatelet agents such as acetylsalicylic acid. If gastrointestinal bleeding or ulceration occurs in patients receiving Ketanov, treatment should be discontinued.

Respiratory dysfunction

Caution is required when using the drug in patients with bronchial asthma (or with a history of asthma), since NSAIDs have been reported to accelerate the onset of bronchospasm in such patients.

Effect on kidney function

Prostaglandin biosynthesis inhibitors (including NSAIDs) have been reported to have nephrotoxic effects. The drug should be prescribed with caution to patients with impaired renal, cardiac, or liver function, since the use of NSAIDs may lead to deterioration of renal function. Patients with minor renal impairment are prescribed lower doses of ketorolac (those that do not exceed 60 mg/day IM or IV), and the renal condition of such patients should also be carefully monitored. As with other drugs that inhibit prostaglandin synthesis, increases in serum urea, creatinine and potassium have been reported during use of ketorolac tromethamine, which may occur after a single dose.

Cardiovascular, renal and liver disorders

The drug is prescribed with caution to patients with conditions that lead to a decrease in blood volume and/or a decrease in renal blood flow, when renal prostaglandins play a supporting role in ensuring renal perfusion. In these patients, renal function should be monitored. The volume reduction should be corrected and serum urea and creatinine levels and the volume of urine excreted carefully monitored until the patient becomes normovolemic. In patients on renal dialysis, the clearance of ketorolac was reduced by approximately half the normal rate, and the final T1/2 increased approximately threefold. Patients with impaired liver function due to cirrhosis did not have any clinically significant changes in ketorolac clearance or terminal T1/2. Borderline elevated values ​​on one or more liver function tests may occur. These abnormalities may be temporary, may remain unchanged, or may progress with continued treatment. If clinical signs and symptoms indicate the development of liver disease or if systemic manifestations are observed, Ketanov should be discontinued.

Fluid retention and swelling

Fluid retention and edema have been reported during use of ketorolac, so the drug should be administered with caution to patients with cardiac decompensation, hypertension, or similar conditions.

Cardiovascular and cerebrovascular effects

There is currently insufficient information to assess such a risk for ketorolac tromethamine. Patients with uncontrolled hypertension, congestive heart failure, diagnosed coronary artery disease, peripheral arterial disease and/or cerebrovascular disease should be under medical supervision.

Systemic lupus erythematosus and mixed connective tissue diseases

In patients with systemic lupus erythematosus and various mixed connective tissue diseases, the risk of developing aseptic meningitis increases.

Dermatological reactions

Ketanov should be discontinued at the first signs of a skin rash, damage to the mucous membranes or any other signs of hypersensitivity.

Anaphylactic (anaphylactoid) reactions

As with the use of other NSAIDs, anaphylactic (anaphylactoid) reactions (including anaphylaxis, bronchospasm, flushing, rash, hypotension, laryngeal edema, angioedema) may occur in patients who have no or no history of hypersensitivity reactions to aspirin, other NSAIDs or ketorolac. This set of symptoms may also occur in individuals with a history of bronchospastic reactivity (eg, asthma) and nasal polyps. Anaphylactoid reactions, such as anaphylaxis, can be fatal. Therefore, ketorolac should not be taken by patients with a history of asthma and patients with a complete or incomplete combination of bronchial asthma, recurrent nasal polyposis and paranasal sinuses, and Quincke's edema. If anaphylactoid reactions occur, seek emergency medical attention.

Hematological effects

Patients with bleeding disorders should not be prescribed Ketanov. Patients receiving anticoagulant therapy may have an increased risk of bleeding if ketorolac is used concomitantly. The condition of patients who are receiving other drugs that can affect the rate of bleeding control should be carefully monitored when prescribing ketorolac. In controlled clinical trials, the incidence of significant postoperative bleeding was less than 1%. Ketorolac inhibits platelet aggregation and prolongs bleeding time. In patients with normal bleeding time, the duration of bleeding increased, but did not go beyond the normal range of 2-11 minutes. In contrast to the long-term effects resulting from the use of acetylsalicylic acid, platelet function returns to normal within 24-48 hours after discontinuation of ketorolac. Ketorolac should not be prescribed to patients who have undergone surgery with a high risk of bleeding or incomplete control of bleeding. Caution should be used if mandatory bleeding control is critical. Ketanov is not an anesthetic agent and does not have sedative or anxiolytic properties; therefore, it is not recommended as a pre-operative sedative to maintain anesthesia.

Use in pediatrics

The drug is not used in children and adolescents under 16 years of age.

Impact on the ability to drive vehicles and operate machinery

Some patients may experience drowsiness, dizziness, vertigo, insomnia, fatigue, blurred vision, or depression when using ketorolac. If the patient experiences the above or other similar side effects, you should not drive or operate machinery.

Danger of use

If used incorrectly and for too long, Ketanov can cause side effects such as:

• Allergic reactions. The condition is manifested by skin rashes, difficulty breathing (less commonly, anaphylactic shock and asphyxia).
• Digestive disorders - constipation, loose stool, flatulence.
• Hypertension.
• Kidney pathologies.

In case of an overdose of the drug, it is necessary to rinse the stomach with plenty of water and take any sorbent.

Side effects

Uncontrolled use of Ketanov can lead to the following side effects:

1. severe headaches, drowsiness, increased nervousness;
2. disruptions in the functioning of the nervous system;
3. depression, sudden mood swings;
4. jumps in blood pressure, slowing of cardiac activity;
5. disruption of the digestive system, which is accompanied by vomiting, nausea, high flatulence, diarrhea, constipation, gag reflex;
6. the appearance of swelling of the legs, arms, face and whole body;
7. difficulty breathing, decreased hearing, ringing in the ears, blurred vision;
8. anaphylactic shock (occurs rarely and mainly with a serious overdose).

Using painkillers in large quantities often leads to serious consequences. For example, problems develop in the functioning of the kidneys, and the proper functioning of the gastrointestinal tract is disrupted.

There are cases when people suffering from severe toothache cannot take Ketanov. This mainly occurs when there is an individual intolerance to the components of the drug or the need for long-term use of painkillers. One of the main reasons for refusal is the dispensing of medications in pharmacies with a prescription.

There are several good analogues to Ketanov.

1. Nimesil. Medicinal pain reliever in powder form. Before use, it should be diluted in warm water and the solution should be drunk;
2. Dolak . Medicine in tablets, a non-steroidal drug with anti-inflammatory properties$
3. Analgin. A standard and popular pain reliever that is always available and cheap.

The listed drugs are sold in pharmacies without a prescription.

• Adolor;
• Ketalgin;
• Ketolorac (medicine in tablets).

Particular attention should be paid to the interaction of Ketanov with other drugs.

If it is used in combination with other medications, there is a high risk of increased side effects or poisoning the body with toxins.

Dangerous medications include anticoagulants (for example, aspirin or heparin), lithium compounds, and similar medications with a similar principle of action.

Compatibility with other drugs

People who additionally take other medications need to pay attention to the drug compatibility of Ketanov. Failure to comply with the rule can lead to serious side symptoms during therapy.

Ketanov is not recommended to be combined:

• With other NSAIDs. In this case, the risk of exacerbation of gastrointestinal pathologies that occur in a chronic form increases. While taking several painkillers, internal bleeding often occurs.
• With acetyl acid and products containing paracetamol as an active ingredient.
• With thrombolytics due to the risk of blood thinning.
• With diuretics. In this case, the therapeutic effect of the two drugs is reduced.
• With insulin. Ketanov enhances the hypoglycemic effect of insulin.

Reviews

Anton, 37 years old. Ketanov toothache tablets act quickly and help eliminate spasms for several hours, but you should not abuse them. If you experience pain, you should contact your dentist as soon as possible.

Irina, 41 years old. At the dacha I got a toothache. I couldn’t see a dentist because I was too far from the city. The pain was so severe that it radiated into the ears and eyes. I took the only painkiller that was in my first aid kit – Ketanov. The product relieved the pain within 15 minutes and allowed me to spend the weekend at the dacha without any problems. I got an appointment with a doctor only 4 days later. The dentist said that I acted irresponsibly, because Ketanov has a lot of side effects.

Vitaly, 38 years old. I can’t speak unequivocally about the drug. I only used it once, when I damaged the root of a tooth. I took it as a preventive measure so that I wouldn’t feel pain later. However, my injury was not accompanied by pain. This drug does not help my brother at all. He says it also hurts to chew food and drink. I think you shouldn’t count on a special therapeutic effect from the drug for serious problems. It's better to go to the dentist right away.

Specifics of Ketanov treatment for toothache

Relief from acute toothache occurs within 30 minutes after taking Ketanov . The analgesic effect lasts for 7 hours. At the first signs of return of pain, repeated administration of the drug is allowed. The maximum dosage is limited to 4 tablets per day.

Severe toothache is often accompanied by inflammatory processes. If it is not possible to immediately consult a dentist, it is recommended to relieve pain with Ketanov. In addition to the analgesic effect, it helps prevent the progression of the inflammatory process and relieve fever.

Blocking the enzymes responsible for the formation of pain does not allow Ketanov to fight muscle spasms. In the line of analogues, Ketanov stands out for its ability to quickly act on the source of unpleasant sensations, the strength of the effect and the rapid removal of tissue swelling.