Nystatin suppositories are an effective remedy against thrush

Composition and release form

in dark glass jars or polymer jars, 20 pcs.; in a cardboard pack 1 jar.

in a blister pack 5 pcs.; in a cardboard pack 2 packs.

in a blister pack of 5 pcs.; in a cardboard pack 2 packs.

in tubes of 30 g; in a cardboard pack 1 tube.

Compound

The active ingredient of Nystatin is a polyene antibiotic. The latter is a natural antimycotic produced by the actinomycete Streptomyces noursei. When taken orally, polyene antibiotics are practically not absorbed from the gastrointestinal tract. External use of these substances also does not result in their entry into the systemic circulation. In addition to the main substance, the drug may contain the following auxiliary components:

• lactose;
• petrolatum;
• potato starch;
• calcium stearate;
• anhydrous lanolin.

Directions for use and doses

Inside, regardless of food intake. Adults: 500,000 units 4–8 times a day. For generalized candidiasis, the daily dose is increased to 6,000,000 units. Children aged 1 to 3 years - 250,000 units 3-4 times a day, over 13 years - 250,000-500,000 units 4 times a day. The course of treatment is 10–14 days. If necessary, the course can be repeated after a week.

Rectally, deep into the rectum, 1 suppository 2 times a day (morning and evening). The course of treatment is 10–14 days. The duration of treatment and the need for repeated courses is determined by the doctor.

Vaginally, after hygienic procedures - 250,000–500,000 units 2 times a day (morning and evening). The course of treatment is 10–14 days.

Locally, the ointment is applied in a thin layer to the affected areas of the skin and mucous membranes 1–2 times a day, daily for 7–10 days. Can be combined with taking the drug orally.

Contraindications

The instructions state that the drug should not be used by children under one year of age. However, Nystatin is still prescribed to infants for severe candidiasis. Pregnant women are recommended to use the antifungal agent in the form of an ointment. When used externally, the drug is not absorbed into the systemic bloodstream and thus cannot cause any harm to the child. Among other restrictions on the use of Nystatin, the instructions indicate:

• breastfeeding period;
• peptic ulcer;
• pancreatitis;
• allergic reaction to individual components of the product;
• severe liver dysfunction.

Reviews about Nystatin

Nystatin tablets, what are they for? This is an antifungal drug used to treat candidiasis , a fungal disease that can occur with damage to the skin, nail plates, mucous membranes and internal organs ( generalized candidiasis ). Candidiasis of the genital mucosa and oral cavity is called thrush. The main method of treating mild to moderate oral thrush is local treatment. Adults can dissolve the tablet after meals 3-4 times a day or lubricate the affected areas of the oral mucosa with ointment. For newborns, a tablet of nystatin 250,000 units is crushed and dissolved in a small amount of water. Drops of the resulting solution are applied to a gauze swab and the areas are treated 3-4 times a day. Children from 2 years of age can be given the drug orally, 1/4 tablet three times a day, and the oral mucosa can be treated with the drug “ Candide ”.

Reviews of Nystatin suppositories for thrush are associated with side effects: increased urination, irritation, burning sensation in the vagina. Women often stopped treatment immediately after the symptoms disappeared, while the pathogen was not eliminated and the symptoms returned after a while. According to many women, these suppositories are not very effective; they believe that the drug is “outdated” and prefer modern antimycotic drugs. There are also reviews that these suppositories were prescribed during pregnancy to treat thrush.

Reviews of Nystatin tablets are most often associated with its prescription for the prevention of dysbacteriosis during long-term use of antibiotics. From the first days of antibiotic treatment, many patients were prescribed 250,000 units 4 times a day. It is effective only for the prevention of intestinal candidiasis, since its systemic absorption is 3–5% and it does not affect fungi outside the intestine. When taking the tablets, side effects were observed in the form of nausea and stool upset. In order to prevent candidiasis infections, this drug is immediately introduced into tablets containing an antibiotic. Thus, Tetracycline with nystatin are used for bronchitis , tonsillitis , furunculosis , tracheitis , cholecystitis , purulent skin infections and acne .

Nystatin ointment was used to treat superficial candidomycosis of the skin and in cases of mild disease, good results were noted. For severe fungal skin infections, local application of ointment alone was not enough and systemic antimycotics ( Fluconazole ) were prescribed.

Nystatin price, where to buy

You can buy nystatin preparations for thrush at any pharmacy, they are available for free sale and you do not need a prescription in Latin, written out by a doctor. Their cost is reasonable. Thus, the price of Nystatin in suppositories ranges from 84-92 rubles, the price of Nystatin in tablets No. 20, 500,000 units. is 20-28 rubles, and the price of Nystatin ointment 30 g is 49-75 rubles.

• Online pharmacies in RussiaRussia
• Online pharmacies in UkraineUkraine
• Online pharmacies in KazakhstanKazakhstan

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Nystatin analogues

Level 4 ATC code matches:
Ecofucin

Primafungin

Clindacin

Polygynax Virgo

Polygynax

Analogs of the polyene series: Levoy , Natamycin ; imidazoles: Ketoconazole , Miconazole , Clotrimazole ; triazoles: Fluconazole , Intraconazole .

Indications for use

For vaginal suppositories

• candidiasis of the vulvo-vaginal area ;
• prevention of fungal diseases with local antibiotic .

For tablets

• prevention of fungal diseases in the postoperative period during operations on the gastrointestinal tract ;
• candidiasis of internal organs of the skin and mucous membranes ;
• prevention of gastrointestinal candidiasis during long-term antibiotic therapy .

Indications for use of ointment

Candidiasis of the skin and mucous membranes .

Negative reactions of the body

When using nystatin suppositories in accordance with the doctor's recommendations and the dosage instructions for use, adverse reactions of the body are rarely observed. Allergic reactions are practically eliminated, since the active component almost does not enter the bloodstream.

Minor local discomfort after using suppositories disappears quickly, so replacement of the drug is not required. Yellowish discharge after using suppositories is considered normal. The main unpleasant symptoms that can persist on the mucous membrane of the vagina or anus for a couple of days are as follows:

• Burning or itching.
• Edema and hyperemia.

A false sensation of the presence of a foreign body may also occur. This is due to swelling. When used rectally, suppositories can provoke a frequent and strong urge to defecate. In some patients, suppositories may cause diarrhea. It can be one-time or maintained for the entire period of use of the candles.

Serious negative reactions of the body can occur in people with weakened immune systems, as well as those suffering from serious kidney and liver pathologies. In such cases, chills, nausea and vomiting may occur after using suppositories. In addition, while taking the drug there is a risk of increased signs of liver failure.

The risks of overdose are not high due to the absorption characteristics of the active substance. But if pronounced negative reactions of the body appear, it is necessary to rinse the stomach and take absorbents.