Nimesil and Ketorol are medications that help get rid of inflammatory processes and intense pain. Both medications belong to the group of non-steroidal anti-inflammatory drugs. It is recommended to consult your doctor before choosing the appropriate option.
Nimesil and Ketorol are medications that help get rid of inflammatory processes and intense pain.
Differences
Ketorol is more often used as a pain reliever: its effectiveness against inflammation is lower than that of Nimesil, so doctors prescribe a more effective medicine. Nimesil can be used as a complex remedy; it helps well both with pain and with infectious processes accompanied by hyperthermia.
Various forms of release. Ketorol can be purchased in the form of tablets or solution for intramuscular injection. Nimesil is sold in powder form for the preparation of a solution for oral use.
Nimesil is less likely to cause adverse reactions. This is often taken into account when choosing a pain reliever.
Medicines have different principles of action. Ketorol inhibits the activity of type 1 and type 2 enzymes that synthesize prostaglandins. Such exposure, however, may negatively affect the functioning of the gastrointestinal tract. The second drug affects only the second type of enzymes; the analgesic effect becomes less pronounced.
Which is better Nise or Ketanov: features and differences
Painkillers are medications based on a medicinal substance that reduce pain, suppress it, or treat it, depending on its properties.
Today we will talk about non-narcotic analgesics. This is a group of drugs that are mainly used for pain caused by inflammation of any organs and tissues. They reduce temperature and have an anti-inflammatory effect. Now let's discuss two specific drugs from this group.
Nise
It is produced in the form of round, smooth, yellowish tablets, as well as in gel form.
The active substance is nimesulide , which reduces fever, pain and fever. Serves as an antioxidant, prevents the formation of toxins, and stops the destruction of collagen.
Begins to act in 30-40 minutes. Well absorbed from the gastrointestinal tract.
This medicine is prescribed for diseases such as psoriatic and rheumatoid arthritis, osteoporosis, inflammation of tendons and ligaments, lumbago, headache and toothache. Does not affect the course of the disease.
Contraindications
Diseases of the gastrointestinal tract, liver, hemophilia, pregnancy and breastfeeding, inflammatory bowel diseases.
When taking Nise, it is better not to use other types of analgesics and ethanol. Elderly people are especially at risk of developing diseases such as stomach and intestinal bleeding, deterioration of the kidneys, heart, and liver. If necessary, medical supervision is required. Possible side effects also include nausea, heartburn, and vomiting.
Another disadvantage is that the presence of a sedative (calming) effect has not been studied; therefore, when taking it, activities that require concentration are not recommended.
Varieties
- Gel.
- Pills.
- Suspension for oral administration.
Different release forms contain different amounts of active substance. A larger amount of nimesulide is contained in tablets - 100 mg in one, and in one gram of gel there is 10 mg.
Ketanov
These are white round tablets, engraved with “KVT”. The main component is tromethamine ketorolac . In addition, it is available in the form of a colorless solution for injection.
Reduces pain, inflammation, lowers temperature. In terms of the degree of pain relief, we compare it with morphine (an organic compound of opium contained in poppy). Does not cause addiction. Does not have a sedative or hypnotic effect.
Contraindications
Nimesil cannot be used for the treatment of intolerance to components, allergic reactions, inflammatory processes in the intestines, fever, viral pathologies, bronchial asthma, recurrent formation of polyps in the nasal cavities, gastric or duodenal ulcers, severe renal, hepatic or heart failure, any pathologies liver. Do not take during pregnancy or lactation. Children under 12 years of age should not be taken. Do not use for alcohol or drug addiction. Do not combine with other NSAIDs.
Ketorol cannot be treated if you have intolerance to the components, allergies, peptic ulcers of the duodenum and stomach, gastric bleeding, inflammatory processes in the intestines, hemophilia, bleeding disorders, cardiac, renal, liver failure, pathologies of the liver and kidneys in the active stage, after coronary artery bypass surgery, before and during surgery, during pregnancy, lactation, and childbirth. Do not use in children under 16 years of age. Do not combine with other NSAIDs containing acetylsalicylic acid.
General indications for the use of Ketonal and Ketanov
Both drugs are non-hormonal, non-narcotic drugs intended to relieve inflammation, relieve pain and reduce fever. They can be in tablets, drops or ointments and gels. As a rule, doctors prescribe these drugs in the following cases:
- In the therapeutic treatment of inflammatory ailments of the musculoskeletal system:
- Osteoarthritis;
- Rheumatoid arthritis;
- Gout;
- Neuralgia;
- Psoriatic arthritis;
- Ankylosing spondylitis.
- To relieve pain: Migraine and acute pain in all parts of the head;
- Severe toothache;
- During treatment of oncological diseases;
- After surgery;
- During renal colic;
- For radiculitis;
- For muscle pain;
- For dislocations and fractures.
It should be noted that these medications can be used regardless of the degree and severity of pain symptoms of different origins. The most popular are creams and gels, which are quickly absorbed into the skin and have a good anti-inflammatory effect, they quickly relieve pain .
In what cases should these painkillers not be used?
It is strongly recommended to begin any use of Ketonal or Ketanov only after consulting a doctor and examining the patient’s complaints and symptoms.
These drugs may be strictly contraindicated in a number of the following diseases and physical conditions:
- Allergic reactions in the form of rhinitis or urticaria due to an overdose of aspirin, diclofenac or ibuprofen;
- Stomach ulcer;
- Inflammatory processes in the intestines;
- Poor blood clotting;
- Impaired kidney and liver function;
- Cardiovascular diseases;
- Internal bleeding of varying severity, regardless of its location;
- Dysfunction of the digestive system;
- From the 28th week of pregnancy;
- Lactation period;
- Children under 16 years old;
- Individual intolerance to the constituent components of drugs.
Taking into account the general health, as well as the general condition of the person, the doctor may significantly reduce the dose of the medicine. As a rule, this occurs if the patient experiences:
- Vegetovascular dystonia;
- Viral hepatitis;
- Kidney failure;
- Diabetes;
- High blood pressure;
- Alcohol addiction.
Any restriction on the use of tablets, ointments or drops will depend on the individual characteristics of the body. It should also be borne in mind that these medications are effective for temporary pain relief and should not be taken to eliminate chronic pain.
Ketonal and Ketanov: differences
The most basic difference between one drug and another is the different active ingredients in their composition . In Ketonal it is ketoprofen , in Ketanov it is ketarolac .
Despite the fact that both components are comparable in effectiveness to morphine, Ketonal is eliminated from the body faster during metabolism, and, accordingly, the number of possible side effects is much less .
This property allows the medicine to be prescribed to older people.
Another significant difference is that Ketonal can be presented in the form of capsules, tablets, as well as gel or suppositories for external use. This means that the drug can be taken with other drugs in relatively small oral doses.
Speaking of effectiveness, Ketanov’s action begins 40 minutes after ingestion and reaches its best effect after two hours, while its analogue is mainly used to relieve chronic long-term pain.
Most common adverse drug reactions
Since the drugs belong to the same pharmacological group, their side effects are mostly the same:
- Stomach upset;
- Increased fatigue;
- Headaches and dizziness;
- Weight gain;
- Swelling of the arms, legs and face;
- Heavy sweating.
In some cases, the patient may experience abdominal pain and vomiting. Depending on the cause of the symptoms, there is an increase in blood pressure, accompanied by severe shortness of breath and hearing dysfunction. In addition, allergic rhinitis and urticaria may occur.
With excessive use of tablets, an overdose may occur, which is manifested by vomiting, hallucinations, drowsiness, and in case of severe poisoning, a stomach ulcer may develop.
Ketonal or Ketanov: which is better?
Since each person is unique by nature, medications will act differently on each person. The choice of the necessary drug, as well as its form, will depend on the symptoms of the disease, as well as after a specialist has examined the necessary tests and examination results.
To eliminate headaches or toothaches, it is best to use Ketanov in the form of tablets or powder. It will quickly relieve symptoms, and in cases of severe pain, you can apply the medicine every 3-4 hours.
For external use, Ketonal in the form of an ointment or gel is well suited. It will relieve swelling and pain in joints and muscles. It is recommended to apply to the affected areas of the body twice a day, and after 3-4 days you can feel the result.
Before purchasing from a pharmacy, they may recommend both Ketonal and Ketanov. It is best to find out the difference in the use of these drugs during a consultation with a specialist. After all, the correct and competent use of medications contributes to a speedy recovery.
Side effects of drugs Nimesil and Ketorol
Nimesil can rarely cause anemia, hemorrhage, and pancytopenia. Allergic reactions are possible: itching, skin rashes, redness of the skin, increased secretion of mucus and sweat. Occasionally, dizziness, anxiety, nightmares, headaches, and drowsiness are observed. Possible decrease in visual acuity, increased blood pressure, increased heart rate. Diarrhea, nausea, vomiting may occur, and less commonly, constipation and flatulence. Gastritis and the formation of peptic ulcers are more rare. There may be blood in the urine.
Taking Ketorol can cause stomach pain, diarrhea, gas formation, constipation, vomiting, nausea, cramps, hepatitis, acute renal failure, and frequent urination.
Taking Ketorol can cause stomach pain, diarrhea, gas formation, constipation, vomiting, nausea, cramps, hepatitis, acute renal failure, frequent urination, nephritis, visual and hearing impairment, rhinitis, laryngeal edema, headaches, dizziness, drowsiness, depression, hallucinations, psychosis, fainting, pulmonary edema, hypertension, nosebleeds, anemia, leukopenia, skin rashes, urticaria, pain at the injection site (during injections), swelling, weight gain, increased sweating, swelling of the tongue.
Patient reviews
Oleg, 34 years old, Kharkov: “The doctor prescribed Nimesil for lower back pain. Took it twice a day for 10 days. The condition has improved greatly, the excruciating pain has disappeared. He combined therapy with folk remedies and special massage. The only negative is that the solution has an unpleasant sour taste.”
Elena, 27 years old, Penza: “The doctor prescribed Ketorol tablets because of severe toothache that appeared even at rest. I felt relief after the first use; The low price of the medicine also became an advantage. I took 2 tablets a day for 3 days. Then the diseased tooth was treated, the pain went away completely.”
